The UK’s National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs; www.nc3rs.org.uk) is an independent scientific organisation, established following a review by the House of Lords, to support innovation in the UK bioscience sector by driving the development of new models and tools with reduced reliance on animals and improved animal welfare.
We work with research funders, academia, the pharmaceutical and chemical industries and regulatory bodies using the 3Rs – Replacement, Reduction and Refinement – as a framework to address global scientific challenges. We are the largest funder of 3Rs research in the UK.